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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41831efc2c7f76e244f6bac7484e93f9cd236ff75b462c2670c71b2ace49657a' 
  AND token = 'XN8SiDh44trsf0Es1peIuMKAN05rnobPtsqtwppG2OY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}