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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8af409c0dbe0d658b4adba952e4e8fee4a22e7d26a5dcb6c6ec503a521bd0628' 
  AND token = 'YXPggUF/fV4aLCF+p7qE1t1sN5mJ3kmfsNzeYKCA/iE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}