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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4cc66c08fa989d9e40691e489113f93b1e9eb48b760ff4b729634f093c229f0' 
  AND token = '+BKA8unAwmQV2oGMFSvKM159dHbXQr1xGC+v4s0fePo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}