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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4963f0e300c054282abfd8f65ae5617d2b99b873e5e6360b218f99314b02ce48' 
  AND token = 'H+i9EKIcW2Ro5no+LkYsWhC24Ux9Om1clrq4pH282Ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}