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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6633f1000efb00bf3bee3d345717e16f67b39805a12b63a8fcb4d327c99b7124' 
  AND token = 'p/i6RQrPkXZBcZRS4obcz/3oavDlBHGG0hg946kmXe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}