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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '531f81e9cd0537ba08249c3e2f667f8b713491e6e82ceb69d2b32c81a730d375' 
  AND token = '6/QMTrXY5byhrCp2qhJXiKt+UIsro/vMr34KofCKtcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}