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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9acf9b662dfc1741d7ee85a61de48657d96c9663b45a34e68c099e9d9c2e0d59' 
  AND token = 'F8NAsII1wcg8dvfAWASIVp3Yya7bozD4cDa8ghOB5WE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}