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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d45db232fd43042fc8aaf6f8f24f7046a4310350934772865d664b67da59799' 
  AND token = '7HS6k9ARxe+9vpaD3WkoEyVemZ8R3b/9BSPBf1f1o7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}