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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '790a2997dc8af075ab795310d18377f32f3e53eb1fd81926d67e54eb8a8da05a' 
  AND token = 'nAeBjEMhrOsEzQ6DiAM8cwm3Ey6M5VaVlQWkXymuHrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}