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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2b431c0b7b3b50f2863a4702822bef505fdb66b39720fdca8554448fe11c096' 
  AND token = 'SlIzVCLmaDLA//tx1Ks1uDKREBoHSnXfCvfCkR+Kiys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}