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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8de1cbf85aa49ca76ca483099297172f0ef970c89cb8f6c84104af9861789068' 
  AND token = 'Zxzxl3qFt2obU4NWA5EnT1RCRVX5g+VV0Jez6Hyn5WM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}