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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b6a208aeefeac5f22d9add65d531cbf7e7d138dcc099eb7f40d3529c1af5319' 
  AND token = '2vMOL6tbgs8e1N1cclYblHq9sa8pRdqEhUqtyF6bXVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}