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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f6501327bd82bafe9256366590cf18d0ac1f239297871746ae4447fdc20d434' 
  AND token = 'AcpaxVUylFO5GMIEOPK+d33+P9lZ2DWX4EXTUEGT9zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}