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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1a266725c1a386cd0a49f1c586d29971ce007c5835e333c58d264099630ff98' 
  AND token = '6fvzpUt7RtoOo6fOJ+rWwjk71A6i+p0LgxMVHammhDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}