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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77380bca5ef5ec73021bc1277490bcf0d8652efdace3aae7e3e0ba2e4d27e4ac' 
  AND token = 'HD01U1+VU5WeiF84JCz7cPdEH7hY8EdtqVOS0sGWXHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}