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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fe66e36c19962736e151965f810e52dcabeeecbe38ec964224f6eed557494c2' 
  AND token = 'hMM00iKASHDWzs4ruDSCXziKFT7yFU0wSNVXAevHl/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}