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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a073344c7c6f6ecc216d1b5fa8bf627808cfe705c8badb91ce651cba7ea1c02' 
  AND token = 'yPYe62oGyi3UbKIB8aIdm0i5tqCMAQZ9v7xoOhqqVOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}