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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1538254ce3d9c09e59b1b34e651928c0471f64c9af4d65128ea5499747c59801' 
  AND token = 'fYX++Xz1SKaK747BQdRH5XjS7VeACmOBcHtDOqV4O/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}