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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '494928f28b7c1b021d1880fb1ad5aea74dd0c993173e88c5aeff3450ed8e3638' 
  AND token = 'G6xslgL7g3n92V40ttWBHoRbYHGf+Rz2dEEa/88DB5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}