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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '726ff3aa4ad2c09c9cad626b7748a9610ace43ccd9778cd8db8d680d1e7ae376' 
  AND token = 'GDLQ2ATULIwVbcXtW8t62JDvawbcuWIZYoF8tP2XO+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}