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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '454d65602246b77c54a85bcc0bf4dd1bf131b76991b87e0e2ee6e362da3546ab' 
  AND token = 'LKeHpuBBsisO4zG1VADtoazvWTh7fscIt+eZC5S3+Jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}