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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ccd4893de8be3492bfcf04290fd1053b7a8a957e69e86863e016f4d4edbf9e0' 
  AND token = '5ASpGO2y7QU0akp8aOAE8VZwiV5zoxpJB2HlgnzyVv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}