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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3536ff5e5ed7722d07ceaed5fe1a1398e8a36a09b03812ab2fb49514b9878189' 
  AND token = '81YlVz09CiE7H+a6kvbG2H0eePD6lza8ZpLSEBJi9Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}