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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f18ab9c1aee7242cd64f86dc8f284ea35a6ba154312898ad0beb102867e9b7' 
  AND token = '1K12b0Py/Y2JQ7JeRFeLGoJQvldko8j6gaCEcJQ2+OU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}