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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c667283f4023b72729837fc3cfb4a723edcb4417f22d543566844483defc435' 
  AND token = 's7B6Tektxsa5tiOWHg0EqU06hcEeKkvmplnYgJakII8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}