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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c11188c994f99bad24a940fbb0a5ec0ec6dc5848c2f143ec59be88e5c59f77a1' 
  AND token = 'ecB1ciwtq/P+mWJ2GSbzM4tYutJX7YNFcY24xvRnOrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}