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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2047eb6866d46c01f67bed95abcf1e21bb77c86db5bce47402a53b69375c7195' 
  AND token = 'El7ryhmle4wU1Qbu1m+2vty1aFAkfY4MJmTTVKb+hH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}