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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b8d6890ab92683104a3d14872427e34cf362bbdc7280bc04fcc9cceb2b13072' 
  AND token = '8tTlyxXNbViA9auX/nACHcMX9ReuC3sDbnfEVl0Dp5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}