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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a280ae185eda6e8865d8e3706f30690e449a645d906559e09a07623d17186fb6' 
  AND token = 'HAZ6/8fiOYNpisNqRwNRCR7HFvG4NrPdfzB7BB1lMYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}