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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64aaafbf2b777fbf825efef8f4f75cbefe8c643863b16a6884f8b7c8126d494e' 
  AND token = '6bhUv78X/TjzaFYKDUBIUphUURS9qFpjYz0Enkgc7uM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}