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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '805477d116b4d5dfabc70639e0efa1be99a7dfaa56d5c61e9b8038adc1e51970' 
  AND token = 'UdiOpID3brC27b8EHSJRx2zFfjXDmR6xMQqjsKjDPDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}