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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77f45e3376ad514d06fc465161f5345d9b62ca6d1c23f3811b7b0c699f318527' 
  AND token = '2VMzsle3tiHKRLeqmk+ef92OYNRckoQn3NVPQmlYLKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}