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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35e49219318fb9be6f009f8ceef22d0146909ca8c884ca930d5c1d9be9f32938' 
  AND token = 'lv1JK2QRSR/sHf+05zYv57ii5aMN+dkQyQsQBGhpHeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}