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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce3ca13cee5c7d22cb268cccc3e2496cf6b82a269a9b15b164ba67261bfc9b81' 
  AND token = 'DxaH277ohpEJ01uv693vPL3uaPnRiGhKEqHg5L+xEdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}