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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '010ead4b9b109008653b1a4102edff3983d1e253ed288f962367c639b5c5d814' 
  AND token = 'TUfACxosqgcgGoBZ/PD4PUVoQgsN49aGRNyeCkcm97g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}