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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae58c284741b6f443595a669cf40229d078e0162ed6d105fcd4aaf98e69b7d9f' 
  AND token = 'qwYR2+eBT+MepoCG3GCl20k51yoYE10mGDcxDKTxjhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}