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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a49765c851981b82c6af24bd07b22b455a4687c9743080e8ad53c8a7928ac71' 
  AND token = 'UQnR0MGIFMoPZ1pvjA27llc6OoVM6IFl0MYuDXJehKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}