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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b38ee6973063896f8b6f3390ad366953aeab2bd45a0509dfac6ad63b9b39fb' 
  AND token = 'KtYX1fjhPON9M1y6ZIXHTfH+5AU1HP9ge0Tyg/qJnZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}