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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a8068ed7a8c843c6d636a105b5f58b5e0752a02f6e8493a7f11daa30d99c0d' 
  AND token = '8Ui4WUsUswlKVQSQomKP9DbsTVKkVTQuSbJWgNRVtJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}