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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d5af20ca20bd602fdc19eeedbc5449a0d1e677ae7c7cdf6521d86e59267a1c4' 
  AND token = 'j4/wC4Lz3lPw9rDd5Oe98pE4Zfur3aBL9SOSDobOi0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}