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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f05a0786769d2371d9199c0394f1b994107ec8d66ff0154ee509a32c505b29c' 
  AND token = 'X2gFKx94aWhVjf/TR7c5Zy4noLPRtg/RTsNBzhtPVGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}