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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a87972f8956fa3e7d5da934a3c883c72f70d69f740a72e8a6bec5a9afe8112a5' 
  AND token = 'YVIDlb04QeV/qFK9ACT+Y094IBS+b0ZK2N7ED6ONuBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}