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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce8c58b81c7337c2627a19b88c6e89f8f5ce0a4fc87e575d86fbfe45d42dfcf2' 
  AND token = '+xePo/AmoA6cDNX9W+SYY9OZ1E2ckoJISRjhKCOU1XI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}