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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '186f5d0a52d40f7cbd71c91d70e6cf525d7b4366134e589f63cf09baf5236e18' 
  AND token = 'j2xlgJT3e6eyz5rOdex1x15y2Nb4qO8ufi83hynQ9Gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}