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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37ab1bbeb8e54d7cccfd0304d29bc585529d3a17e49b785ee8e7fd9d04778f6f' 
  AND token = 'HxqiUZR+LILPFDYwAk9XZGM2Z5F8UEkp0buob1Sb4AY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}