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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ad85309c72896c74134f741d3a4d036dbc7b5b032333e9fed531453851df8c1' 
  AND token = 'T0BRsVSdGxDaEh6JRhULNNullgO0j1cy1/5p2YsZ+r8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}