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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0cdd2725339335e9545a18af386fa12ff4a2d4d8ac646a1d8e778e3449dd5d4' 
  AND token = 'Kq3yVA/2WLsFcVN013gmh/zqzHd+WZMoVSDCq7K4mWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}