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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c4cc23a15c4e96ca4b213ddfd012abdd21d05fdd3c4dce0fcf671952955651c' 
  AND token = '+/OGW2z/nENL4EvuBe6NMW8i2sL60b9shKt5oMgqlgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}