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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cad270bacd5a4774e5248e2e4601f609ba56c4ff6a84e9ce62b246d9725baa00' 
  AND token = 'DEhKbDyiXcgn5Fa1wV7/14UZXtX84SUXLsrRCH0JA0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}