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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b84511f68e2cf91e8a372597a0afa61825b3b4e871c4defd40825ca69d6c338' 
  AND token = 'y4KUrF0j9XckPmIa7VQwB3H3eTQbx+Z5XrEMc/ciLAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}